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Does Autosomal-dominant Polycystic Kidney Disease affect Blood Pressure?

Autosomal dominant polycystic kidney disease is an inherited disorder characterized by the presence of genes in an individual. Yearly, millions of people are affected with autosomal dominant PKD, which is characterized by the presence of innumerable cysts on the kidneys.

As the cysts grow in size and number, ADPKD results in the enlarged size of the kidneys. This increased size kidney may not function well and results in end-stage renal disease if not managed well. Most people with ADPKD may survive well with an ayurvedic approach and lead a normal life until the symptoms relapse once again.

One of the most prevalent comorbidities of ADPKD is high blood pressure. High blood pressure or hypertension is the increased flow of blood against the wall of the blood vessels.

How does ADPKD affect blood pressure?

Autosomal dominant PKD can affect blood pressure in two ways:

  • By damaging blood vessels’ linings
  • By secreting hormones that control blood pressure

The genes that trigger the occurrence of ADPKD are not only important for kidneys but are also found in the blood vessels linings. When these genes lose their function, they disrupt the way blood vessels tighten and relax. In people with ADPKD, blood vessels have a different mechanism of tightening and narrowing themselves. They tend to be smaller than usual, which means confined space for the blood to flow willingly.

Unhealthy kidney function due to ADPKD can also activate hormones that control blood pressure. Although there are a number of reasons these hormones may get activated- kidney cysts can damage tiny blood vessels in the kidneys, making it harder for the blood to flow through them. As this happens, the hormone levels in the body rise as the body tried to get more blood.

High blood pressure tends to worsen as the kidneys tend to lose their function with the progression in ADPKD.

Since poorly controlled blood pressure can further damage your kidneys, it is essential to get it under control. Here are some tips that may help:

Make some lifestyle changes

  • The first step in managing high blood pressure is to opt for a healthy lifestyle.
  • Lose weight if you need. Improving weights help improve blood pressure.
  • Exercise: Being physically active with some exercise regime can actually work on your cholesterol.
  • Limit alcohol. If your doctor has suggested limiting alcohol and caffeine, do that!
  • Quit smoking. There is an undeniable link between smoking and high blood pressure.
  • Lower your stress levels. Try to identify your stress triggering elements. Be sure to take enough sleep and enjoy your tie in relaxing activities.

Consume a healthy diet

People with PKD are recommended a renal-friendly diet to manage signs and complications such as hypertension. Sodium is essential- agreed, but too much sodium in your diet can be unhealthy. It results in fluid retentions. Similarly, try to include fresh fruits and vegetables instead of frozen foods packed with too much sodium.

Take blood pressure medications as suggested by the doctor

Many people with polycystic kidney disease and hypertension need to take medications. Talk to your doctor about the things that you should adhere to while taking these medications. While taking ayurvedic treatment for ADPKD, you may also get benefitted from hypertension. Ayurvedic medications help manage the complications and symptoms linked with ADPKD.

Does ADPKD increase the risk of other cardiovascular problems?

People with ADPKD are at an increased risk of multiple comorbidities, especially if blood pressure is not controlled.

These may include:

  • Hardening and narrowing of the arteries, known as atherosclerosis
  • Stiffening of the walls of the heart’s left side
  • Building of the blood vessel in the brain called brain aneurysm

These conditions put you at the risk of potentially fatal problems such as abnormal heart rhythm, stroke, heart palpitations, and heart attack.

If you have PKD, we recommend ayurvedic treatment to prevent the risk of life-threatening morbidities. Ayurveda has the potential to bestow life to patients suffering from various chronic disorders.

Get to us to know more!


Disclaimer: Consult the ayurvedic doctor before consuming ayurvedic medications and have the ayurvedic treatment under a well-certified ayurvedic kidney care hospital. For further advice, you can use this helpline: +91-9821929797 number or visit www.karmaayurvedahospital.com.

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Certificate no- AH-2023-0186

JAN 05,2023-JAN 04,2026