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What is Pyuria?

Pyuria is a condition related to the presence of white blood cells in the urine. Through naked eye WBCs cannot be witnessed, but you will notice the urine to have a cloudy appearance because of pus.

The only way to identify pyuria is through a urine test. In order to determine or examine pyuria, you must have at least 10 white blood cells in each cubic millimeter of urine. This is a type of infection. Pyuria often occurs as a result of urinary tract infection or sepsis.

In sterile pyuria, you may have white cells counts even without having any sign of bacterial infection.

Related: Anemia treatment in Ayurveda

What are the causes of pyuria?

Pyuria can occur because of many reasons the most common of which is urinary tract infection.  The urinary tract system is an infection in the parts of the urinary tract system, including such as the kidneys, ureters, urethra, and bladder.

On the other hand, sterile pyuria is caused by sexually transmitted infections, such as viral infections or gonorrhea.

A urinary tract infection is another cause of Pyuria.

The other causes of pyuria may include:

  • sexually transmitted diseases (STDs)
  • viral infections such as adenovirus, BK polyomavirus, and cytomegalovirus
  • painful bladder syndrome
  • pelvic infections
  • intra-abdominal infections
  • interstitial cystitis
  • pneumonia
  • interstitial cystitis
  • sepsis
  • radiation cystitis
  • urinary fistulas
  • foreign bodies in the urinary tract
  • transvaginal mesh
  • intrinsic renal diseases
  • renal transplant rejection
  • tuberculosis
  • polycystic kidney disease
  • kidney stones
  • fungal infections
  • autoimmune diseases, such as Kawasaki disease

The long-term use of the following drugs can also cause pyuria. Following are the medicines which should not over-consume for a long time:

  • antibiotics with penicillin
  • aspirin
  • diuretics
  • olsalazine
  • nitrofurantoin
  • non-steroidal noninflammatory drugs, such as ibuprofen
  • proton pump inhibitors

Related: Are you on the risk of CKD

What are the possible signs of pyuria?

The most prevalent signs of pyuria can be cloudy urine or urine with pus. The urine color changes because of the presence of an increased number of white blood cells.

If UTI is recurring and persistent, you will notice:

  • frequent urges to urinate
  • Inability to empty the bladder
  • burning sensation when urinating
  • blood in urine
  • Smelly urine
  • Pain in pelvic area
  • High fever

Other symptoms that may persist include:

  • Discharge
  • Pain in the bladder
  • Nausea or vomiting

However, pyuria may also persist without any alarming sign and cause no symptom. This is why it is essential to be highly active in annual checkups. Delaying the diagnosis and treatment ultimately will lead you to a greater risk of life-threatening conditions.

Related: Your Carbohydrate Count During CKD

Are there any risk factors involved?

A female is more at risk of pyuria than men do. It is also common in older adults. Sterile pyuria is common in elder women as their estrogenization levels decrease by this time. Similarly, menopause is also a common factor linked to the occurrence of pyuria as there is a risk of UTI during menopause.

If you are sexually active, even then your risk of developing pyuria increases because of the likelihood of UTI.

Diagnosing pyuria

The doctor takes a urine sample to analyze urine. The lab technician will examine whether the urine has bacteria, pus, white blood cells, etc. During pyuria, white blood cells are present in every sample but bacteria may or may not. The number of WBCs and bacteria will help the doctor know the cause.

A urinary tract infection is only identified with the help of leukocytes or nitrites. If there is no UTI, the doctor will look for WBCs counts.


The treatment to cure pyuria involves treating the underlying cause. A UTI can be treated with home remedies and antibiotics or ayurvedic treatment. If fungus is the root cause, your doctor may prescribe you antifungal medicines.

For more information on conditions related to the kidneys, you can consult Karma Ayurveda Hospital.


Disclaimer:- The purpose of the content on this page is not to substitute any professional medical advice but to only provide information to the reader. If the reader is a kidney patient, we recommend not making any diet or routine changes without consulting his/her doctor or dietitian. For appointments, call at our 24×7 helpline: +91-9871712050 or visit www.karmaayurvedahospital.com

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